Translocation chromosome map of oncogenes.

The chromosome territory of human oncogenes.

The prevailing view of the chromosome of higher organisms is characterized by randomness. Genes are believed to be located at random and mutations and most structural rearrangements are likewise supposed to occur at random (1-4). During the last few years the molecular organization of the eukaryotic chromosome has been subject to intensive investigation but the evidence has been mainly on singl...

variant complex chromosome translocation with chronic

a large number of simple or complex translocation involving the cml and aml chromosomal abnormalities has been described. this study was aimed to investigate the complex chromosome aberrations in the series of myeloid malignancies including cml and aml. the present report deals analyzed 187 consecutive with cml and aml patients, using methotrexate  cell synchronization and  un-stimulated cultur...

Acute leukemia with C-G chromosome translocation.

characterized by a specific chromosomal marker (the Philadelphia chromosome, Ph’), a significant percentage of all morphologic types of leukemia, except possibly chronic lymphocytic leukemia, will demonstrate aneuploidy. This report describes the occurrence of acute lymphocytic leukemia (ALL) in a young man with a balanced C-G translocation, t(Cp; Gp+), a rare chromosomal abnormality not previo...

Comprehensive linkage map of bovine chromosome 27.

The results of genotypic data contributed to the International Society for Animal Genetics (ISAG) Bovine Chromosome 27 Workshop are presented. Eight laboratories contributed 23 261 informative meioses from 44 loci. Eighteen loci were typed by at least two laboratories and were used to construct a consensus linkage map. Twenty-one loci were subsequently incorporated into a comprehensive map. The...

A linkage disequilibrium map of chromosome 22